Run's amazing, 50+ FPS on Windows 8 in windowed mode; go to SE5 folder/data/HUDSettings and edit Width and Height. When you run SE5, click Setup and change Display Drive to your graphics cards, Video mode to Windowed, Video memory usage to Safe. (Graphics and Background left on High ;)).
Nvidia Settings for SE5 executable Manage 3D settings, Program Settings:
Maximum pre-rendered frames: 1
Power management mode: Prefer Maximum Performance
Triple buffering: On
Vertical sync: On
Dunno how much of the above is necissary or if it actually did anything, but the above is what I cobbled together from over the interwebs to get good fps.
AND DO NOT FORGET TO D/L BALANCE MOD!
Also, toss in some shipsets and spice it up.