Now I've never played a Shadowrun game before, however I'm not exactly new to turn based/strategy RPG games, having played games in a similar vein like the Shin Megami Tensei: Devil Survivor series and Fire Emblem. However, I'll be the first to admit I'm far from a veteran in the genre.
One of the key things I think Returns did right, is the tricky task of drawing me into the story immediately. It's pretty simple: your friend is dead, he's left you a "dead man's switch" - a recorded message promising a hefty reward if you can find the killer. OK. I'm in.
As for the ease of playing the game... as someone who's often daunted by complex RPG interfaces with endless choices, decisions, and items to equip, I thought Shadowrun's interface is a breeze. It clearly shows you your weapon slots, inventory slots, and which body parts you can equip on armor or modifications. As for playing the game itself, you can simply click on your HUD to switch between weapons or end turns, but there are hotkeys for the more practiced player, too.
You encounter many characters on your way to solve your friend's murder, and you get to pick and choose your own team of Shadowrunners to go on every mission with you. Each has their own specialty - summoning mechs, specializing in "decking" (hacking), melee combat, guns, magic, and so on, and I had a great time testing out all the different classes.
All of the characters have their own specialties, but the game is forgiving, and you could probably get by just using guns on everyone. I realized one of my runners had a healing ability 3/4 of the way through the game, and had been getting by just fine without knowing that. So if you're worried about difficulty or complexity, don't be.
Another positive for me is the game is heavily text based. There is a lot more discovery and reading than combat. You can also save anywhere except an NPC turn in combat, or in conversation. So I could get up to answer the door or grab some food without bothering to pause, or quit at a moment's notice if my friends asked me to play a multiplayer game.
I know I'm writing a review no one will ever read, for a two year old game, but it gets an easy recommendation from me, especially if you're a busy person who can only enjoy games in bits and pieces before you're on the go again.