Being fans of all things Puzzle Quest, we've just turned on support for Steam Cloud to it and its cousins. This means you'll be able to continue your quest from any machine when launching the Steam version of the following games:

Puzzle Quest 2
Puzzle Quest: Challenge of the Warlords
Puzzle Quest: Galactrix
Puzzle Kingdoms
Puzzle Chronicles

And don't forget that Puzzle Quest 2 is currently 33% off on Steam! If you already own the game, feel free to purchase multiple copies for your friends.