Real chemistry, not fantasy alchemy. Combine substances, fill your codex, take quizzes, hunt reactions, and play rhythm challenges in Substance Lab POL.

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About This Game

Real chemistry. Not fantasy alchemy.

Substance Lab POL is an educational chemistry game grounded in real scientific information—not magical potions or invented fantasy recipes. You combine substances based on real chemical reactions, study real materials, and learn through practice.

Crafting, quizzes, and rhythm modes share one goal: help you explore chemistry that actually exists in the real world.

Combine with real chemistry

Mix elements and compounds using combinations inspired by real reactions and formulas. Discover substances the way chemistry works—through structure, properties, and workable equations—not random fantasy crafting.

Build a growing library of real-world materials as you unlock new results through experimentation. Easy mode can hint at the reaction type; Hard mode asks you to name it first. Each attempt uses a combination stone.

Solve problems and quizzes

Test what you have learned with formula quizzes, element quizzes, and Find reaction. Problem-solving sits at the center of the experience, so progress comes from understanding—not only from collecting icons.

Rhythm challenges

Switch to rhythm minigames for short, focused sessions between study and crafting. Choose a track and difficulty. A different pace, same lab.

Periodic table and textbook

Browse all 118 elements, study groups and periods, and open a textbook of reaction types with examples from the lab.

Features

  • Combination gameplay based on real chemistry
  • Easy and Hard reaction modes
  • Formula quiz, element quiz, and Find reaction
  • Rhythm minigames with songs and difficulty
  • Full 118-element periodic table and textbook
  • Growing library of unlocked substances
  • Interface in 13 languages
  • Windows and macOS

Who is it for?

Players who want a chemistry learning game—not a fantasy alchemy RPG. If you like combining real substances, answering chemistry questions, and mixing in light rhythm play, this lab is for you.

AI Generated Content Disclosure

The developers describe how their game uses AI Generated Content like this:

This game uses generative AI for some music tracks. No AI content is generated during gameplay.

System Requirements

Windows
macOS
    Minimum:
    • Requires a 64-bit processor and operating system
    • OS: Windows 10 64-bit
    • Processor: Dual-core 2.0 GHz or better
    • Memory: 2048 MB RAM
    • Graphics: Integrated graphics (Intel HD / AMD)
    • Storage: 500 MB available space
    • Sound Card: Any
    Recommended:
    • Requires a 64-bit processor and operating system
    • OS: Windows 10 / 11 64-bit
    • Processor: Quad-core 2.5 GHz or better
    • Memory: 4096 MB RAM
    • Graphics: Dedicated or modern integrated GPU
    • Storage: 1000 MB available space
    • Sound Card: Any
    Minimum:
    • OS: macOS 11.0 (Big Sur) or later
    • Processor: Apple M1 or Intel Core i5
    • Memory: 2048 MB RAM
    • Graphics: Integrated graphics
    • Storage: 500 MB available space
    • Sound Card: Any
    Recommended:
    • OS: macOS 12.0 or later
    • Processor: Apple M1 or Intel Core i5
    • Memory: 4096 MB RAM
    • Graphics: Integrated graphics
    • Storage: 1000 MB available space
    • Sound Card: Any
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