COMBINE WEAPONS in the microscopic roguelite turret shooter with macroscopic depth. Survive 6 modes using an astounding array of turrets, perks, mutations and power-ups on this psychedelic journey to the heart of the abyss. Shmup Mode turns it into a vertical shoot 'em up!
Gameplay | Trailer
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Curator Review

Recommended
By Wanderbot June 29, 2024

“A 'simple' wave defense Roguelite that actually has layers of content hidden away for players to discover. The weapon upgrade system and build variety is top tier.”

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About This Game

Dive into the microscopic world, radiating with bioluminescent life and unspeakable horrors. Genome Guardian is a deeply-complex shooter that's easy to pick up but hard to master. Research permanent upgrades to survive a variety of microbes across 6 game modes, each with multiple "depths".

Pair DNA nucleotides Adenine (rapidfire), Cytosine (precision), Guanine (spread), Thymine (explosive) to discover wild hybrid bioweapons!

  • Bomb + Shotgun combines explosives with spread to create Blast Shotgun!

  • Bomb + Bomb doubles down on explosive power to make Bazooka!

  • Blast Shotgun + Shotgun forms the all-powerful Flak Cannon!

  • 49 Turrets with unique strengths and functions

  • 96 Perks to mix and match that drastically change how you play

  • 75 Weapon & Turret Mods that can turn shots into sticky laser mines or bouncing fireballs

  • 64 Mutations alter the challenges you face each run

  • 20-minute Runs that can be continued in Endless Mode

  • 75 Bassy Electronic Tunes that adapt to the current mood & intensity

  • Cosmetics like spider legs and tank tread

  • Accessibility Settings for colourblindness, motion sickness, and even arachnophobia!

  • 100 Steam Achievements

  • Steam Trading Cards

  • Cloud Save

  • Plays great on Steam Deck!!!

System Requirements

    Minimum:
    • OS: Windows 10
    • Storage: 800 MB available space
    • Additional Notes: Change Quality / Render Scale in SETTINGS if low FPS
    Recommended:
    • OS: Windows 10
    • Storage: 800 MB available space
    • Additional Notes: Change Quality / Render Scale in SETTINGS if low FPS

Customer reviews for Genome Guardian About user reviews Your preferences

Overall Reviews:
Very Positive (651 reviews)






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