COMBINE WEAPONS in the microscopic roguelite turret shooter with macroscopic depth. Survive 6 modes using an astounding array of turrets, perks, mutations and power-ups on this psychedelic journey to the heart of the abyss. Shmup Mode turns it into a vertical shoot 'em up!
Gameplay | Trailer
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Buy 🧬 Genome Guardian × Nubby's Number Factory ③: Roguelike Combo BUNDLE (?)

Includes 2 items: Includes 2 items: Genome Guardian, Nubby's Number Factory

-15%
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Buy 🧬 Genome Guardian × Rocket Rats 🧀: Survival Roguelikes BUNDLE (?)

Includes 2 items: Includes 2 items: Genome Guardian, Rocket Rats

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Includes 2 items: Includes 2 items: Genome Guardian, Galactic Glitch

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About This Game

Dive into the microscopic world, radiating with bioluminescent life and unspeakable horrors. Genome Guardian is a deeply-complex shooter that's easy to pick up but hard to master. Research permanent upgrades to survive a variety of microbes across 6 game modes, each with multiple "depths".

Pair DNA nucleotides Adenine (rapidfire), Cytosine (precision), Guanine (spread), Thymine (explosive) to discover wild hybrid bioweapons!

  • Bomb + Shotgun combines explosives with spread to create Blast Shotgun!

  • Bomb + Bomb doubles down on explosive power to make Bazooka!

  • Blast Shotgun + Shotgun forms the all-powerful Flak Cannon!

  • 49 Turrets with unique strengths and functions

  • 96 Perks to mix and match that drastically change how you play

  • 75 Weapon & Turret Mods that can turn shots into sticky laser mines or bouncing fireballs

  • 64 Mutations alter the challenges you face each run

  • 20-minute Runs that can be continued in Endless Mode

  • 75 Bassy Electronic Tunes that adapt to the current mood & intensity

  • Cosmetics like spider legs and tank tread

  • Accessibility Settings for colourblindness, motion sickness, and even arachnophobia!

  • 100 Steam Achievements

  • Steam Trading Cards

  • Cloud Save

  • Plays great on Steam Deck!!!

System Requirements

    Minimum:
    • OS: Windows 10
    • Storage: 800 MB available space
    • Additional Notes: Change Quality / Render Scale in SETTINGS if low FPS
    Recommended:
    • OS: Windows 10
    • Storage: 800 MB available space
    • Additional Notes: Change Quality / Render Scale in SETTINGS if low FPS

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