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In Iosis, you control the Silver Guard, which protects the Vitriol Vessel from waves of corrupted metals with collisions. The main source of damage is momentum; the higher the velocity and mass, the higher the damage. As you progress through fast-paced runs, you will have the opportunity to improve your play style according to several themes, focusing on mobility, self-sacrifice, manipulation and more.

Iosis is inspired from bullet hell and tower defense genres with a special emphasis on customizable runs that allow unique builds. Dying as the Silver Guard is only a temporary setback which unlocks builds that depend on self-damage and unleashes devastating power.

• Collision-based close combat: The core combat depends on the momentum of the player as the main damage source. Basically, the faster you move, the higher the damage you deal. Becoming a massive object is also a way to increase your damage output but be careful not to restrict your mobility too much.

  

• Over 60 collectible upgrades: In Iosis, the collectible upgrades come in two categories: Active spells and passive residues. Residues are of various types; parametric upgrades, periodically activated effects, triggered effects based on collisions and dash movement to name a few. Spells are more versatile and can be picked up and gotten rid of throughout a run to customize your build.
  

• Over 20 different enemies: There are a number of metallic enemy types, Iron, Copper, Mercury, etc., each specializing on an aspect of gameplay. You will need to develop defensive mechanisms to negate their combat advantages.
  
  

• 3 linearly progressive stages: The three layers of purification are abstracted in these layers: Gates, Fountains and Towers. You will find the difficulty of the game increasing as you progress through these layers.
  
  

• Unique environmental challenges: As you progress through the abstract planes of alchemy, you will encounter different environments presenting unique challenges and rewarding permanent upgrades.
  

Play as the guardian of the Vitriol Vessel, the essential substance to achieve enlightenment and purity through the stages of alchemical space. You will face base metals that seek to corrupt the vitriol, for all metals have a lust to reach the purest of all, gold. Your main source of defence is your momentum, through mobility and strength, you must seek higher wisdom and purification.