Midkine (MDK) also known as neurite growth-promoting factor 2 (NEGF2) is a protein that in humans is encoded by the MDK gene.

Midkine is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin (NEGF1, 46% homologous with MDK). It is a nonglycosylated protein, composed of two domains held by disulfide bridges. It is a developmentally important retinoic acid-responsive gene product strongly induced during mid-gestation, hence the name midkine . Restricted mainly to certain tissues in the normal adult, it is strongly induced during oncogenesis, inflammation and tissue repair.

MDK is pleiotropic, capable of exerting activities such as cell proliferation, cell migration, angiogenesis and fibrinolysis. A molecular complex containing receptor-type tyrosine phosphatase zeta (PTPζ), low density lipoprotein receptor-related protein (LRP1), anaplastic leukemia kinase (ALK) and syndecans is considered to be its receptor.

This is the sequel to that.

Definitely a yes to recommend,
I think I got the full version of this like right before they completely stopped vendoring Dreamcast games like in 2003 or 2004. (was gonna get Fur Fighters but that didn't happen) I actually beat this game growing up, maybe spending more than 20 hours playing it.
Looking back now, and currently STRUGGLING to beat Kurts second level I don't see how I did it as a kid. The game does have it's difficult moments but nothing too hard. Literally probably only Kurt's second level (you'll see what part when you get to it)
Because of crap like that I do miss the checkpoints instead of having to save my own my own when I find a safe area.

Haven't played with keyboard yet but the Xbox controller having like an EXTREMELY similar mapping/design to the DC controller made it SUPER easy to adjust... just didn't like having to map things myself (but I'm just lazy)
Sadly partial controller support I believe is a thing so (RB and LB) v (LT and RT) you'd have to go with buttons because If youre jumping and shooting with the triggers cancelling an action is going to happen... so its choosing one or the other. That seeming to be my only controller issue... sensitivity varies from player to player on analog.

The game's story is wacky and comical, something I find enjoyable but probably a bit too wacky and corny even as I was growing up.
A great ending to a great story with none of that twist crap but let me shut my mouth before i start spoiling
4/5

One word: EPIC

the sa2 of third person shooters

Not as good as the first MDK, but still full of fun and clever ideas. The best one is using all three characters, each with a different skills.

Awesome game, that brings good memories.
3 colorful main characters, mad story and explosive gameplay without explosive barrels.
God bless Bioware and Interplay.