A surprisingly decent game that is perfect for some short term casual play, Elder Sign: Omens appears based off a boardgame, but has made a fairly good transition into a video game. The player takes control of four investigators and chooses who they will be dealing with, with each adventure having their own opponents with their own effects on the game. At first, you'll find easy tasks to do in your home museum. Later adventures expand past the museum, letting you go to other locations as well as giving you entirely new tasks. These adventures can be played in any order as well.
While I can not say I know the original boardgame, it does appear to have been four player. It seemed odd at first that they would turn it into a singleplayer game then, but after some playing I can safely say that the four investigators only barely interact with eachother, so instead of four players each playing a fourth of a game, they instead have one player playing the whole thing. Controls are not awful either, as one would expect from a boardgame made into a video game.
If you do not like random chance, this may not be something for you. The entire game exists of smaller adventures, in which you get what are essentially dice and need to match dice with the situation's requirements to pass. You may be lucky and complete a difficult quest in one try, or you may spend 3 turns failing at one of the simplest ones. Luckily, you have items and investigator special powers that will help you get through them. In the end, you will always have an element of random chance in it, but even then, it's a pretty good way to spend some time during slow periods.
And, of course, Lovecraft. The adventures have plenty of flavour to them and seem to be pretty close to how one would play through a Call of Cthulhu game, although clearly with less pen and paper roleplaying stuff and with more singleplayer set-in-stone stories that you can progress through.
Ph'nglui mglw'nafh Cthulhu R'lyeh wgah'nagl fhtagn
Be sure to keep him that way, it would be a shame if he woke. Humanity probably wouldn't like it. And you're probably part of humanity.