Summer in Mara is a relaxing farming sim, featuring the protagonist Koa who - as all of us should - goes on summer adventures constantly barefoot.

Portal (1) is an first-person game where you traverse obstacle courses using a portal gun and if at first you don't succeed, you fail. The protagonist is barefoot through-out the game.

ARK is a game about gathering, building, taming dinosaurs and often getting eaten. All characters start with only a loincloth. Additional clothing is useful but not required.

Oblivion is an RPG in The Elder Scrolls universe. The game allows you to simply not equip footwear. The loss of stats is usually negligible.

Skyrim is an RPG in The Elder Scrolls universe. The game allows you to simply not equip footwear. The loss of stats is usually negligible.

Morrowind is an RPG in The Elder Scrolls universe. The game allows you to simply not equip footwear. The loss of stats is usually negligible.

GTA SA is a story-based / sandbox 3rd person shooter where police enforcement may want to have a talk to you. Wardrobe lets you customize your looks, including removing footwear.

Guild Wars 2 is a MMORPG. You can either omit wearing footwear (leading to lower stats) or find/purchase a (rare/expensive) armor transmog rendering footwear invisible.

Diablo 4 is a top-down action RPG with lots of loot. The game allows you to hide whatever piece of armor you want, allowing for a fully barefoot character from start to finish.

Overwatch 2 is a team-based shooter with a big roster of heroes to choose from. Each hero has a set of cosmetic "skins" and some of these are barefoot. Notable examples: Sigma, D.va, Moira.