This review is for the realMYST version and not the game Myst in general, that game is recommended many times over for any fan of adventure games.
This game is a full 3D remake of the original, with much better graphics that the original and I had it running in full 1080p resolution. Some people have complained about some texture issues, but I haven't noticed it, but it is possible that there is more graphics quality inconsistency than the original, but everything is still better than the original. I found that having fluid movement helped my immersion of the game.
Some people have complained about the game's controls, personally I found them better than the original. You can adjust several control settings such as mouse speed and dead zone size in the options to suit your needs. I found the game easier to play when using just the mouse and ignoring the keyboard, left clicking to move forwards.
Be aware that some people have had some compatibility issues with the game; you should be able to get the game running, except maybe with some bugs. Expect more issues if you have a 64bit system. I personally ran the game with Windows XP SP3 32bit and the game ran perfectly for me, so if you can fall back to an XP system, that will work for you. I will update the review when I upgrade to Windows 10 64bit.
I would recommend this version of Myst to any newcomer of the series. The only issue is that it doesn't cater to nostalgia as much as the original version, so if you are playing the game purely for a nostalgia trip; you might prefer the Myst Masterpiece Edition.