This game reminds me of Caeser, Pharoah, and the other economy-based city-builders of the 90's and early 2000's. I haven't played any other Anno games so I cannot comment on if this is a good or bad Anno game, but I've really enjoyed it. You have to build a city while managing a bunch of different resources, which are used to upgrade your city and advance up the technology chain. You can only get certain resources from some islands, so you need to either expand your empire or trade with other players. It's a little complex, and it can get very overwhelming in the late game when you are dealing with many islands and every resource, but it's really satisftying when everything clicks into place and you have a functioning chain of islands.
The big downside is the Uplay DRM. It's actually problem-free for me, but I can't deny that it is utterly useless. It runs in the background for no real reason, and you need to sign up for a Uplay account. If you're lucky like I am, that's all the interaction you'll need to do with Uplay. I know some people have an avalanche of problems, so your mileage may vary.
Get the Deep Sea expansion, because it adds a whole new faction to the game and it feels incomplete without it.
I'm not sure if the campaign really goes anywhere, and the bulk of the game seems to be based around the sandbox-esque continuous game mode. So, if you're looking for goals and missions, you might want to look elsewhere. If you like managing cities and supply lines, and micromanagement is your game, you'll probably have a great time here.