After playing for several hours, all I can conclude about this game is that it's excessively frustrating.
First off, the tutorial lacks a lot of important information. No mention that you have to build aesthetic stuff all over to keep up morale, no proper explanation of what most of the structures/objects do or why you should care about them. I lost three bases to everyone flipping out on each other before I pulled up the (terribly-made) wiki and a starter's guide said to scatter cosmetic stuff everywhere to keep people happy.
The interface, while thematically good at first, gets very old very fast. Every UI element is oversized, and everything flickers like an old TV set with every interaction, and everything has horizontal lines through it like an old computer monitor. It gets grating and hard on the eyes rather quickly. Event warnings on the right side of the screen can be minimized (usually), but not dismissed, even for minor alerts, or ones that no longer apply.
You have no direct control over the citizens of your station, which is fine, but it means that when they're all ignoring your orders - which happens fairly often - you can't do anything about it. The closest you can get to controlling anyone is setting people to the "security" job and setting a beacon - they'll jog over and stand near the beacon, but that's all you can do. You can't prioritize commands, or set a "do this first" type thing on anything, so if you need a room built NOW, you have to go across the entire map and cancel every other build/dismantle task. If things fall into disrepair, technicians take FOREVER to fix them - each time they work on something, they only improve it by a few percentage points, and then wander off again. You also can't set anyone to do more than one task - a guy can build things, or repair things, but not both unless you constantly toggle his settings in the roster screen.
Raiders and derelict ships spawn far too often and too regularly - it's not at all random. If you don't get "security" to respond in time to raiders, your citizens will just wander through and drop one by one. Seriously, multiple times I've lost almost my entire station's population to single raiders because nobody has the sense to run away when they're being shot at, or security gets there one at a time and just drops.
A known bug (I'd say it's a bug, anyway) with derelict ships is that sometimes they'll just "drift away" with your people still on-board. What this means is that the derelict despawns - taking your people with it. This means you have to very quickly "claim" every part of the derelict to prevent that, at which point it's treated like part of your base - including constant alerts that it's not connected to the power grid, and citizens will wander over to it and just hang about, making it impossible to safely dismantle. This also includes warnings about rooms on the ship not being tended to properly, even if you've already flagged everything to be dismantled for materials. Heaven forbid you don't tend the garden on that ship you plan to scrap (by the way, it mentions this only in passing in the tutorial, but you NEED a garden - it provides food that doesn't eat through your resources like the food-dispenser does. And you need a bar with full facilities to serve/store that food properly - also only hinted at).
Researching new technologies/illnesses isn't discussed at all in the tutorial, nor does it say how gardens work, or what to do with incapacitated-but-alive raiders. It doesn't talk about building a brig, or whether you can ever do anything with these raiders - you only find out on third-party guides that EVENTUALLY these raiders can convert to citizens if they're confined long enough. And your own citizens will freely wander through the brig, even if occupied, and get injured/killed by captured raiders.
"Passing ships" also happen like clockwork, and get spammy. The sense of humor in all the dialogue is great and everything, but it wears thin after the 200th ship in a 2-hour session, especially since most of the somewhat-limited encounter types seem to play out the exact same way every single time - either they give you more citizens, or they send raiders. If you tell them to go away, they either go away, send citizens anyway, or send raiders anyway. And you almost always know exactly what it'll be the moment it pops up. Passing ships also turn off timelapse - you'll be going along at 4x speed to get something built, then it pops back to 1x so you can tell some guy to bugger off because you have no more room for more people. And he may still send more citizens, in which case you have to quickly build beds/rooms for them to stay in or they'll start throwing tantrums and send station morale into the toilet.
I'm sure there are other issues I've forgotten to mention, but I think this gives a decent idea of how obnoxious this game is to play in general.