Before people get angry, yes I like AVGN, I like challenging platformers, I like chiptune music and 8-bit grapichs, etc. and I really really wanted to like this game.
However, I am also of the opinion that if you are parodying something by doing the same thing ironically and then charging money for it, you are still doing the same thing as the thing you parody, and there lies the real problem: strip away the funny presentation and this is the very type of game that James Rolfe makes fun of in his videos, a game filled with fake difficulty to artificially pad out the play time.
Yes, I get it, it's meta jokes, and the jokes are fun... the first time, then comes the major grind to actually beat the levels with insane unfair difficulty. The levels are fairly well designed in of themselves and are amusingly parodying many of the games reviewed on the show, but the platforming controls are rather stiff, hitboxes are often bigger/smaller than they look and obviously the game does everything to kill you as much as possible, though not in a funny "invisible block near a pit" kind of way which would give it a bit of a puzzle element, here it's just by throwing a lot of ♥♥♥♥ at you at once and having you deal with it through sheer pressure.
Also while other fake difficulty parody games like I Wanna Be That Guy at least have the decensy to not throw you back to the beginning unless you pick the higher difficulties when you die, here it does just that on everything but Easy when running out of extra lives which I find to be a major flaw from a modern perspective, no matter how retro or thematically appropriate it is. And before you say "just go play on Easy then", I would if it didn't give me more HP than normal, make bosses stupidly easy to beat and lock off several achivements, which obviously isn't very enjoyable, and it still doesn't fix the hitbox and stiff controller issue.
Ignoring the difficulty, the game is also rather short. If you get good at this I could imagine you would be able to beat the entire thing in 2-3 hours, though it does have a fair ammount of hidden secrets and replay value for the really really hardcore crowd when you unlock the truly ridicolous difficulty levels, so it's not that big of a problem, but still worth noting.
Basically, if you don't mind NES games that beat your ♥♥♥ with fake difficulty to the max and aren't affraid to start from the beginning of a stage (or the game itself) every time you die, you will probably love this game. Fans of AVGN may also appreciate the referencial humor to both the show itself and the games that he have played. However, the game still isn't up to modern standards in many respects, and it is rather hypocritical, and therefor I cannot recommend it to everyone. It's basically an extremely niche title with a (relatively) mass appeal brand attached to it, but if you don't fall into that niche it might not be worth the frustration no matter how much you like AVGN. If Steam had a "middle" option I would have picked that, but for now I am sad to say I will have to give it a thumbs down personally.
Also, I think James did a disadvantage to the game by reviewing it himself and showing off all the best bits in the video, made playing the actual thing feel a bit less special.