After playing total of ~30 hours and in fact finishing the game with every unique weapon, unfortunately I don't recommend this title.
Let's start from the good side. You have very nice voice-acting, awesome graphics (especially rain visuals on street is pretty damn good, I liked that), and... yeah, that's it.
For some reason I couldn't find more pros. It's a very simple mix of strategy and RPG, with turn-based combat. Gameplay is pretty damn boring, it takes some time in every mission to "settle up" and make a good income, only to discover that 5 minutes later mission is finished... And you start again...
Actually there's no real reason for "having fun" with doing anything apart from main storyline. The only things, which are permanent are the weapons, and most of them are useless anyway.
I won't lie if I say that I had higher hopes for this title. I love Tropicos and got this game as a preorder special to Tropico 5, and decided that I can play it a bit before Tropico 5 arrives, but no. Game is unfortunately boring, repeatable, very short (you can finish it with collecting most of the achievements under 20 hours, on normal gameplay it's about 10-15 hours I'd say), and doesn't really offer ANYTHING, which could potentially hold me for a bit longer.
Sorry Kalypso, but Omerta isn't your strongest title. Adding more RPG elements like taking 1/10 or even less of daily income to the next mission would make it far more enjoyable. There's no real reason for making anything apart from storyline, and perhaps collecting some interesting weapons, but even this is pretty optional. I had higher hopes for this game and I was sure that it will be similar as with Tropico - I start playing and it forces me to finish every damn mission, only because it's that good game. In this case, I had to force myself to finish this game, and it's unlikely that I'll launch this game ever again.